How was the AIPMT re-test in 2015


Personal data
Name Prof. Dr. med. Olaf Hiort
born at 07/03/1961 in Otterndorf, Germany
Institution University of Lübeck
Institute / Department Clinic for Children and Adolescent Medicine, Section for exp. Pediatric
Endocrinology and Diabetology
Address Ratzeburger Allee 160
City, ZIP Code 23564 Lübeck
Phone + 49-451-500 2191
Fax + 49-451-500 6867
e-mail [email protected]
Education / training
1983-1989 Medicine at University of Hamburg and Tufts University of Medicine, Boston
1990-1999 Training in Pediatrics, subspecialties Neonatology, Pediatric Endocrinology and
Diabetes, and Laboratory Diagnostics
Research Experience / Academic Appointments
1991-1992 Post-doctoral fellowship at Harvard Medical School, Boston
Since 2001 Professor of Pediatrics, University of Lübeck
Fields of Natural history and pathophysiology of complex rare endocrine disorders;
Interest namely disorders of sex development and pseudohypoparathyroidism
Important Scientific Prices / Functions
2001-2005 Head, DFG Clinical Research Group KFO 111 “From Gene to Gender”
2003-2009 Deputy Head, BMBF-Network of Rare Diseases “Disorders of Sex Development
2008-2011 Coordinator, FP7 Project EuroDSD (201444)
2010-2013 Member, European Commission of Experts of Rare Diseases
Since 2013 Coordinator, FP7 COST Action DSDnet (BM1303)
IF last 5 years: 165.
Main publications on the topic last 4 years
Hiort O. The differential role of androgens in early human sex development.BMC Med. 2013 Jun
24; 11: 152. doi: 10.1186 / 1741-7015-11-152
Hiort O, Wünsch L, Cools M, Looijenga L, Cuckow P. Requirements for a multicentric multidisciplinary
registry on patients with disorders of sex development. J Pediatr Urol. 2012 Dec; 8 (6): 624-8
Grötsch H, Kunert M, Mooslehner KA, Gao Z, Struve D, Hughes IA, Hiort O, Werner R. RWDD1
interacts with the ligand binding domain of the androgen receptor and acts as a coactivator of androgen
dependent transactivation. Mol Cell Endocrinol. 2012 Mar 2. [Epub ahead of print]
Werner R, Kulle A, Sommerfeld I, Riepe FG, Wudy S, Hartmann MF, Merz H, Döhnert U, Bertelloni S,
Holterhus PM, Hiort O. Testosterone synthesis in patients with 17β-hydroxysteroid dehydrogenase 3
deficiency. Sex Dev 2012 Mar 2. 6 (4): 161-8.
Koehler B, Kleinemeier E, Lux A, Hiort O, Grüters A, Thyen U; the DSD Network Working Group.
Satisfaction with Genital Surgery and Sexual Life of Adults with XY Disorders of Sex Development:
Results from the German Clinical Evaluation Study. J Clin Endocrinol Metab. 2011 Nov 16.
Holterhus PM, Bebermeier JH, Werner R, Demeter J, Richter-Unruh A, Cario G, Appari M, Siebert R,
Riepe F, Brooks JD, Hiort O (2009). Disorders of sex development expose transcriptional autonomy of
genetic sex and androgen-programmed hormonal sex in human blood leukocytes. BMC Genomics. Jul
Appari M, Werner R, Wünsch L, Cario G, Demeter J, Hiort O, Riepe F, Brooks JD, Holterhus PM (2009).
Apolipoprotein D (APOD) is a putative biomarker of androgen receptor function in androgen insensitivity
syndrome. J Mol Med. 87 (6): 623-32.
Werner R, Zhan J, Gesing J, Struve D, Hiort O (2008): In-vitro characterization of androgen receptor
mutations associated with complete androgen insensitivity syndrome reveals distinct functional deficits.
Sex Dev 2: 73-83